Chemosensitivity相关论文
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Inhibition of survivin expression and mechanisms of reversing drug-resistance of human lung adenocar
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Drug resistance gene expression and chemotherapy sensitivity detection in Chinese women with differe
Objective:The aim of the study was to identify specific chemosensitivity drugs for various molecular subtypes of breast ......
Inhibition of survivin expression and mechanisms of reversing drug-resistance of human lung adenocar
Background Survivin, a member of the inhibitor of apoptosis protein (IAP) family, overexpresses in tumor cells and not e......
Silencing of high mobility group A1 enhances gemcitabine chemosensitivity of lung adenocarcinoma cel
Background The high mobility group A1 (HMGA1) proteins are architectural transcription factors found to be overexpressed......
目的探讨肿瘤抑制因子CYLD提高膀胱癌细胞吉西他滨化疗敏感性。方法构建CYLD过表达质粒转染的人膀胱癌细胞株T24、253J,将细胞分为......
目的:探索晚期非小细胞肺癌(NSCLC)中ERCC1和Survivin对铂类化疗疗效的预测价值。方法:96例晚期NSCLC患者经免疫组化(IHC)检测ERCC......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Objective:To investigate the feasibility of chemosensitivity testing of antitumor drugs by flow cytometry in clinical ap......
Objective:To evaluate correlation between chemosensitivity of tumor cells in vitro and their clinical responsiveness in ......
in vitro....
Epidermal growth factor enhances chemosensitivity of colon cancer by inducing cancer stem cells to e
Objective The aim of the study was to investigate whether colon cancer stem cells induced by epidermal growth factor(EGF......
DIFFERENCE IN BIOLOGICAL CHARACTERISTICS AND SENSITIVITY TO CHEMOTHERAPY AND RADIOTHERAPY BETWEEN IN
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
在肿瘤化疗中,药物所致DNA损伤起着极其重要的作用.其损伤很大程度上刺激了DNA修复能力的增强,从而严重制约化疗药物的药效.而DNA......
Enhanced chemosensitivity of p73α gene transferred into H1299 cell line of human lung adenocarcinoma
Objective: To study the effects of transferred wild type p73α gene on the sensitivity to the chemotherapeutic agents an......
DIFFERENCE IN BIOLOGICAL CHARACTERISTICS AND SENSITIVITY TO CHEMOTHERAPY AND RADIOTHERAPY BETWEEN IN
Objective To investigate and compare the biological characteristics and sensitivity to chemotherapy and radiother-apy of......
目的 探讨胃癌肿瘤组织中S100P的表达水平对患者预后及肿瘤化疗敏感性的影响及其可能机制.方法 回顾性分析2003年1月至2007年12月......
目的 观察中期因子(MK)基因小干扰RNA(siRNA)对膀胱癌细胞化疗药物敏感性的影响.方法 设计合成3个MK siRNA,转染人膀胱癌RT4细胞株......
目的 探讨乳腺癌体外化疗敏感性的检测(ATP-TCA法)与P-糖蛋白(P-gp)、谷胱甘肽S转移酶-π(GST-π)及TopoisomeraseⅡ(TopoⅡ)表达......
Objective: To investigate the relationship between the expression of p73α and p53 versus the chemosensitivity in breast......
To isolate an isogenic radioresistant cancer cell line after fractioned X-ray radiation and characterize the resistant c......
Effects of glucocorticoids on the growth and chemosensitivity of carcinoma cells are heterogeneous a
AIM: To determine how glucocorticoids (GCs) may affect the growth and chemosensitivity of common carcinoma cells.METHODS......
Background Monolayer cell culture models are the traditional culture models used for in vitro research of pancreatic car......
Inhibition of survivin expression and mechanisms of reversing drug-resistance of human lung adenocar
Background Survivin, a member of the inhibitor of apoptosis protein (IAP) family, overexpresses in tumor cells and not e......
Silencing of high mobility group A1 enhances gemcitabine chemosensitivity of lung adenocarcinoma cel
Background The high mobility group A1 (HMGA1) proteins are architectural transcription factors found to be overexpressed......
目的了解干扰素α(IFN-α)对骨肉瘤U2OS细胞化疗敏感性的影响。方法细胞分为对照组、IFN-α组、顺铂组和IFN-α+顺铂组,处理72 h,......
目的探讨靶向MDM2基因的反义寡核苷酸(ASON)对MCF-7细胞株乳腺癌紫杉醇药物敏感性的影响。方法人工合成一段针对MDM2 mRNA的反义寡......
目的:观察冷冻联合5-Fu对G422胶质瘤化疗敏感性的影响,并探讨其内在的分子机制.方法:建立G422胶质瘤动物模型,随机分组,分别施以化......
目的探讨小片段干扰RNA(siRNA)干扰NF-E2相关因子2(NF-E2-related factor 2,Nrf2)对人喉癌Hep2细胞化疗敏感性的影响及凋亡的差异。方......
目的:观察叉头转录因子M1(forkhead box protein M1,FoxM1)基因小干扰RNA(small interfering RNA,siRNA)对大肠癌细胞化疗药物敏感......
目的探讨胰岛素能否增强人宫颈癌Hela细胞对顺铂(DDP)的化疗敏感性及其相关机制。方法体外培养人宫颈癌Hela细胞株,MTr法检测5U/L胰岛......
目的 探讨不同化疗敏感性浆液性卵巢癌组织中BRCA1的表达水平及介导BRCA1表达的表观遗传学分子机制。方法选取化疗敏感与化疗耐药......
目的:研究胃癌体外化疗药物敏感性与临床疗效的关系,为临床肿瘤化疗个体化提供依据.方法:用改进的MTT法测定98例胃癌组织的化疗药......
目的:探讨胸苷酸合成酶( thymidylate synthase,TYMS)在胰腺癌细胞中mRNA表达差异及其表达水平与胰腺癌细胞化疗敏感性的关系。方法:使......
目的探讨外源性P53基因转染对人肝癌细胞系HepG-2化疗敏感性的影响.方法将人野生型P53基因表达载体导人HepG-2细胞中,经筛选和鉴定......
目的探讨EGCG对肺癌耐药细胞株A549/DDP对顺铂敏感性的影响及作用机制。方法MTT法检测EGCG对A549/DDP细胞药物敏感性的影响。AO/EB......
目的:探讨三磷酸腺苷生物荧光法(ATP—TCA)检测非小细胞肺癌对化疗药物的敏感性及其指导化疗的价值。方法:ATP—TCA法体外检测41例非小......
目的:探讨应用RNAi技术下调survivin基因对人卵巢癌SKOV3细胞增殖、凋亡及顺铂敏感性的影响。方法:构建survivin基因shRNA真核表达载......
目的:探讨表皮生长因子受体(epidermal growth factor receptor,EGFR)对胃癌细胞SGC7901化疗敏感性及细胞中信号转导和转录因子3(STAT3......
目的:探讨人恶性肿瘤培养细胞抗癌基因P53功能状态与化疗敏感性的关系.方法:采用大肠癌、肺癌、食管癌、多发性骨髓瘤、白血病5种......
目的观察慢病毒介导的基因干扰对胃癌SGC-7901细胞中E型钙黏附蛋白(E-cadherin)表达抑制效果,及E-cadherin基因抑制对5-氟尿嘧啶(5-Fu......
目的:分析肾脏肿瘤化疗药物的体外敏感性.方法:对19例肾脏肿瘤手术切除标本进行常规MTT药敏试验,检测临床常用的16种化疗药物的体......
背景与目的:本文研究了不同个体乳腺癌细胞对八种抗癌药物的化疗敏感性.材料与方法: 根据临床血浆高峰浓度(1 PPC),41例乳腺癌细胞......
观察分次外照射对小细胞肺癌NCI-H446细胞系药物敏感的影响并探讨其机制.采用GWGP80型远距离60Co治疗机对进入指数生长期的NCI-H44......
目的研究大肠癌体外化疗药物敏感性与临床疗效的关系,为临床肿瘤化疗个体化提供依据.方法用改进的MTT法测定5 3例结、直肠癌组织的......
目的:研究结肠腺癌细胞株经不同化疗药物诱导后Fas/FasL表达与癌细胞凋亡的关系,探索敏感化疗药物的筛选.方法:将顺铂、丝裂霉素、......
背景与目的:信号转导因子与转录激活因子3(STAT3)是近期研究较多的一种基因,在多种实体瘤如乳腺癌、胃癌和卵巢癌等中均有异常表达和......